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The ADC therapy jointly developed by astrazeneca and Daiichi Sankyo has submitted a marketing application to the FDA.
On November 13, Gelonghui announced that astrazeneca and Daiichi Sankyo have submitted a Biologics License Application (BLA) for their jointly developed Trop2 targeted antibody-drug conjugate (ADC) datopotamab deruxtecan (Dato-DXd) based on feedback from the usa FDA, seeking accelerated approval for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations, who have previously received systemic treatment (including EGFR targeted therapy).