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UpStream Bio (UPB)

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  • 6.190
  • +0.270+4.56%
Trading Jun 17 13:08 ET
336.86MMarket Cap-2.13P/E (TTM)

Earnings

Revenue Breakdown

Financial Indicators

Income Statement

Balance Sheet

Cash Flow

UpStream Bio (UPB) Cash Flow

Quarterly+Annual
YOY yoy
Hide blank lines yoy
(Q1)Mar 31, 2026
(FY)Dec 31, 2025
(Q4)Dec 31, 2025
(Q3)Sep 30, 2025
(Q2)Jun 30, 2025
(Q1)Mar 31, 2025
(FY)Dec 31, 2024
(Q4)Dec 31, 2024
(Q3)Sep 30, 2024
(Q2)Jun 30, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities
-16.24%-47.85M
-125.23%-133.28M
-56.18%-30.63M
-59.29%-22.24M
-388.29%-39.24M
-134.40%-41.17M
-56.02%-59.17M
-21.74%-19.61M
-189.73%-13.96M
-8.04M
Net income from continuing operations
-48.85%-40.59M
-128.39%-143.44M
-99.88%-42.46M
-111.03%-33.75M
-172.29%-39.97M
-150.32%-27.27M
-205.82%-62.81M
-79.51%-21.24M
-415.54%-15.99M
---14.68M
Depreciation and amortization
13.95%49K
111.24%188K
16.33%57K
228.57%46K
223.08%42K
230.77%43K
48.33%89K
250.00%49K
-17.65%14K
--13K
Other non cash items
12.69%151K
120.96%561K
11.45%146K
1,687.50%143K
527.27%138K
104.72%134K
82.52%-2.68M
115.82%131K
100.17%8K
--22K
Change In working capital
24.17%-11.35M
-68.55%589K
687.78%7.75M
1,138.35%8.88M
-116.81%-1.07M
-287.57%-14.97M
143.51%1.87M
67.28%-1.32M
-76.55%717K
--6.34M
-Change in receivables
-878.72%-366K
89.32%-55K
350.00%15K
361.86%254K
-262.72%-371K
107.34%47K
-264.01%-515K
-103.59%-6K
44.89%-97K
--228K
-Change in prepaid assets
19.64%-11.05M
-51.19%-1.52M
400.96%6.29M
1,005.21%7.85M
-192.28%-1.91M
-707.58%-13.75M
83.84%-1.01M
64.92%-2.09M
-75.86%710K
--2.07M
-Change in payables and accrued expense
118.68%213K
-22.56%2.73M
80.43%1.6M
982.35%920K
-66.54%1.36M
23.95%-1.14M
107.59%3.53M
-63.11%884K
-89.27%85K
--4.06M
-Change in other current liabilities
-15.67%-155K
-324.81%-565K
-40.19%-150K
-847.37%-142K
-504.35%-139K
-509.09%-134K
-62.20%-133K
-435.00%-107K
135.19%19K
---23K
Cash from discontinued investing activities
Operating cash flow
-16.24%-47.85M
-125.23%-133.28M
-56.18%-30.63M
-59.29%-22.24M
-388.29%-39.24M
-134.40%-41.17M
-56.02%-59.17M
-21.74%-19.61M
-189.73%-13.96M
---8.04M
Investing cash flow
Cash flow from continuing investing activities
119.87%42.4M
-57.15%-93.48M
40.65%58.94M
3,319.87%48.19M
110.95%12.77M
-1,640.43%-213.38M
28.19%-59.49M
899.47%41.91M
-88.50%1.41M
-116.65M
Net PPE purchase and sale
----
67.71%-165K
70.81%-54K
80.37%-64K
----
----
-254.86%-511K
---185K
---326K
----
Net investment purchase and sale
119.87%42.4M
-58.23%-93.32M
40.16%59M
2,680.98%48.25M
110.99%12.82M
-1,640.43%-213.38M
28.69%-58.97M
903.00%42.09M
-85.84%1.74M
---116.65M
Cash from discontinued investing activities
Investing cash flow
119.87%42.4M
-57.15%-93.48M
40.65%58.94M
3,319.87%48.19M
110.95%12.77M
-1,640.43%-213.38M
28.19%-59.49M
899.47%41.91M
-88.50%1.41M
---116.65M
Financing cash flow
Cash flow from continuing financing activities
1,858.82%598K
-99.42%2.44M
-99.59%1.1M
146.31%760K
-99.56%612K
-100.36%-34K
223.36%418.91M
203,594.74%270.65M
-3,382.00%-1.64M
140.52M
Net common stock issuance
--598K
--0
----
----
----
--0
--272.72M
----
----
----
Net preferred stock issuance
----
--0
--0
--0
----
----
15.83%149.92M
--0
--0
----
Proceeds from stock option exercised by employees
----
1,456.60%2.48M
3,839.29%1.1M
3,900.00%760K
512.00%612K
--0
34.75%159K
--28K
-81.00%19K
--100K
Net other financing activities
----
99.13%-34K
--0
--0
--0
-100.36%-34K
---3.9M
---2.1M
---1.66M
---9.51M
Cash from discontinued financing activities
Financing cash flow
1,858.82%598K
-99.42%2.44M
-99.59%1.1M
146.31%760K
-99.56%612K
-100.36%-34K
223.36%418.91M
203,594.74%270.65M
-3,382.00%-1.64M
--140.52M
Net cash flow
Beginning cash position
-68.79%101.77M
1,162.28%326.09M
118.33%72.36M
-3.56%45.65M
126.93%71.51M
1,162.28%326.09M
51.50%25.83M
-29.96%33.14M
18.82%47.34M
--31.51M
Current changes in cash
98.09%-4.85M
-174.71%-224.31M
-89.96%29.41M
288.15%26.71M
-263.36%-25.85M
-4,584.41%-254.58M
3,318.96%300.25M
1,463.48%292.94M
-289.76%-14.19M
--15.83M
End cash Position
35.54%96.92M
-68.79%101.77M
-68.79%101.77M
118.33%72.36M
-3.56%45.65M
126.93%71.51M
1,162.28%326.09M
1,162.28%326.09M
-29.96%33.14M
--47.34M
Free cash flow
-16.24%-47.85M
-123.58%-133.44M
-55.00%-30.69M
-56.10%-22.3M
-388.88%-39.29M
-134.40%-41.17M
-56.77%-59.68M
-22.89%-19.8M
-196.49%-14.29M
---8.04M
Currency Unit
USD
USD
USD
USD
USD
USD
USD
USD
USD
USD
Accounting Standards
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
Audit Opinions
--
Unqualified Opinion
--
--
--
--
Unqualified Opinion
--
--
--
(Q1)Mar 31, 2026(FY)Dec 31, 2025(Q4)Dec 31, 2025(Q3)Sep 30, 2025(Q2)Jun 30, 2025(Q1)Mar 31, 2025(FY)Dec 31, 2024(Q4)Dec 31, 2024(Q3)Sep 30, 2024(Q2)Jun 30, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities -16.24%-47.85M-125.23%-133.28M-56.18%-30.63M-59.29%-22.24M-388.29%-39.24M-134.40%-41.17M-56.02%-59.17M-21.74%-19.61M-189.73%-13.96M-8.04M
Net income from continuing operations -48.85%-40.59M-128.39%-143.44M-99.88%-42.46M-111.03%-33.75M-172.29%-39.97M-150.32%-27.27M-205.82%-62.81M-79.51%-21.24M-415.54%-15.99M---14.68M
Depreciation and amortization 13.95%49K111.24%188K16.33%57K228.57%46K223.08%42K230.77%43K48.33%89K250.00%49K-17.65%14K--13K
Other non cash items 12.69%151K120.96%561K11.45%146K1,687.50%143K527.27%138K104.72%134K82.52%-2.68M115.82%131K100.17%8K--22K
Change In working capital 24.17%-11.35M-68.55%589K687.78%7.75M1,138.35%8.88M-116.81%-1.07M-287.57%-14.97M143.51%1.87M67.28%-1.32M-76.55%717K--6.34M
-Change in receivables -878.72%-366K89.32%-55K350.00%15K361.86%254K-262.72%-371K107.34%47K-264.01%-515K-103.59%-6K44.89%-97K--228K
-Change in prepaid assets 19.64%-11.05M-51.19%-1.52M400.96%6.29M1,005.21%7.85M-192.28%-1.91M-707.58%-13.75M83.84%-1.01M64.92%-2.09M-75.86%710K--2.07M
-Change in payables and accrued expense 118.68%213K-22.56%2.73M80.43%1.6M982.35%920K-66.54%1.36M23.95%-1.14M107.59%3.53M-63.11%884K-89.27%85K--4.06M
-Change in other current liabilities -15.67%-155K-324.81%-565K-40.19%-150K-847.37%-142K-504.35%-139K-509.09%-134K-62.20%-133K-435.00%-107K135.19%19K---23K
Cash from discontinued investing activities
Operating cash flow -16.24%-47.85M-125.23%-133.28M-56.18%-30.63M-59.29%-22.24M-388.29%-39.24M-134.40%-41.17M-56.02%-59.17M-21.74%-19.61M-189.73%-13.96M---8.04M
Investing cash flow
Cash flow from continuing investing activities 119.87%42.4M-57.15%-93.48M40.65%58.94M3,319.87%48.19M110.95%12.77M-1,640.43%-213.38M28.19%-59.49M899.47%41.91M-88.50%1.41M-116.65M
Net PPE purchase and sale ----67.71%-165K70.81%-54K80.37%-64K---------254.86%-511K---185K---326K----
Net investment purchase and sale 119.87%42.4M-58.23%-93.32M40.16%59M2,680.98%48.25M110.99%12.82M-1,640.43%-213.38M28.69%-58.97M903.00%42.09M-85.84%1.74M---116.65M
Cash from discontinued investing activities
Investing cash flow 119.87%42.4M-57.15%-93.48M40.65%58.94M3,319.87%48.19M110.95%12.77M-1,640.43%-213.38M28.19%-59.49M899.47%41.91M-88.50%1.41M---116.65M
Financing cash flow
Cash flow from continuing financing activities 1,858.82%598K-99.42%2.44M-99.59%1.1M146.31%760K-99.56%612K-100.36%-34K223.36%418.91M203,594.74%270.65M-3,382.00%-1.64M140.52M
Net common stock issuance --598K--0--------------0--272.72M------------
Net preferred stock issuance ------0--0--0--------15.83%149.92M--0--0----
Proceeds from stock option exercised by employees ----1,456.60%2.48M3,839.29%1.1M3,900.00%760K512.00%612K--034.75%159K--28K-81.00%19K--100K
Net other financing activities ----99.13%-34K--0--0--0-100.36%-34K---3.9M---2.1M---1.66M---9.51M
Cash from discontinued financing activities
Financing cash flow 1,858.82%598K-99.42%2.44M-99.59%1.1M146.31%760K-99.56%612K-100.36%-34K223.36%418.91M203,594.74%270.65M-3,382.00%-1.64M--140.52M
Net cash flow
Beginning cash position -68.79%101.77M1,162.28%326.09M118.33%72.36M-3.56%45.65M126.93%71.51M1,162.28%326.09M51.50%25.83M-29.96%33.14M18.82%47.34M--31.51M
Current changes in cash 98.09%-4.85M-174.71%-224.31M-89.96%29.41M288.15%26.71M-263.36%-25.85M-4,584.41%-254.58M3,318.96%300.25M1,463.48%292.94M-289.76%-14.19M--15.83M
End cash Position 35.54%96.92M-68.79%101.77M-68.79%101.77M118.33%72.36M-3.56%45.65M126.93%71.51M1,162.28%326.09M1,162.28%326.09M-29.96%33.14M--47.34M
Free cash flow -16.24%-47.85M-123.58%-133.44M-55.00%-30.69M-56.10%-22.3M-388.88%-39.29M-134.40%-41.17M-56.77%-59.68M-22.89%-19.8M-196.49%-14.29M---8.04M
Currency Unit USDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Accounting Standards US-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAP
Audit Opinions --Unqualified Opinion--------Unqualified Opinion------
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